Bioorganic and Medicinal Chemistry Letters p. 1409 - 1414 (1997)
Update date:2022-08-04
Topics:
Azami, Hidenori
Barrett, David
Tanaka, Akira
Sasaki, Hiroshi
Matsuda, Keiji
Sakurai, Minora
Matsumoto, Yoshimi
Tawara, Shuichi
Chiba, Toshiyuki
Sakane, Kazuo
The synthesis and biological activity of the novel series of 1β-methylcarbapenems 1 are described. Most compounds displayed extremely potent antibacterial activity and high renal DHP-I stability. The best compound in this series, FR21818 (1a) displayed ex
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Doi:10.1021/jacs.6b03757
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(1969)Doi:10.1016/S0277-5387(96)00599-2
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(1968)Doi:10.1021/ja9710924
(1997)