Concise synthesis of 3,4-dihydro-1,4-benzoxazines by three-component reactions of acyl chlorides, o-aminophenols and 1,2-dichloroethane

DOI: 10.1016/j.tet.2018.05.037

Source and publish data:

Tetrahedron p. 3691 - 3696 (2018)

Update date:2022-08-02

Topics:

Authors:

Liu, Yunyun

Chen, Xuwen

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Article abstract of DOI:10.1016/j.tet.2018.05.037

The Cu(OAc)₂-catalyzed three-component reactions of o-aminophenols, acyl chlorides and 1,2-dichloroethane (DCE) have been established for the efficient synthesis of 3,4-dihydro-2H-benzo[b][1,4]oxazines (3,4-dihydro-1,4-benzoxazines). This metho

Full text of DOI:10.1016/j.tet.2018.05.037

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