Intramolecular Alder ene approach to stereochemical control over three contiguous stereogenic centres: Synthesis of (±)-methyl cucurbate and (±)-methyl epijasmonate

Article abstract of DOI:10.1016/0040-4039(94)85038-0

The total synthesis of epijasmonoids, (±)-methyl cucurbate and (±)-methyl epijasmonate is described starting from aldehyde 14, where the key step is a highly stereocontrolled 5-(3,4) ene cyclization 17→18.