Journal of Organic Chemistry p. 4615 - 4625 (1985)
Update date:2022-08-02
Topics:
Evans, Ben E.
Rittle, Kenneth E.
Homnick, Carl F.
Springer, James P.
Hirshfield, Jordan
Veber, Daniel F.
A stereocontrolled synthesis of the hydroxyethylene dipeptide isosteric unit 1 is described.This synthesis is capable of providing all eight stereoisomers of 1 and is amenable to variation of substituents R1 and R2.Also described are the novel chiral epoxides 2 and substituted γ-lactones 3, key intermediates in this synthesis having potentially broad application.
View MoreBeijing Mesochem Technology Co.,LTD
website:http://www.mesochem.com
Contact:0086-10-57862036
Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Changsha Yonta Industry Co., Ltd.
Contact:+ 86-731-8535 2228
Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
Hubei Xinghuo Chemical Co., Ltd.,
Contact:13925817279 13907299441
Address:Xinghuo Fine Chemistry Industrial Park, Xiaochang County, Hubei Province, China
Nanyang Tianhua pharmaceutical Co.,Ltd.
Contact:+8618639816203
Address:Longsheng Industrial Park
Huangshi Meifeng Chemical Co.,ltd.
Contact:+86-714-6516706
Address:1941-4-3#,Hubin Avenue,Huangshi,Hubei,China
Doi:10.1002/ejoc.201701150
(2017)Doi:10.1021/acs.orglett.6b01291
(2016)Doi:10.1021/jo970913k
(1997)Doi:10.1002/ijch.199700008
(1997)Doi:10.1039/a806037a
(1998)Doi:10.1039/c39810000492
(1981)
