Diastereoselective, one-pot synthesis of γ-amino alcohols from ketimines

DOI: 10.1055/s-2001-15146

Source and publish data:

Synlett p. 1109 - 1112 (2001)

Update date:2022-07-29

Topics:

Authors:

Veenstra

Kinderman

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Article abstract of DOI:10.1055/s-2001-15146

Deprotonation of ketimines with lithium diisopropyl amide, followed by reaction with aldehydes and subsequent reduction with aluminium hydrides gave γ-amino alcohols with moderate to good syn selectivity. The scope and limitations of this preparative meth

Full text of DOI:10.1055/s-2001-15146

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