
Tetrahedron Asymmetry p. 1987 - 1999 (1997)
Update date:2022-08-03
Topics:
Hulst, Ron
Broxterman, Quirinus B.
Kamphuis, Johan
Formaggio, Fernando
Crisma, Marco
Toniolo, Claudio
Kellogg, Richard M.
Two cyclo-dipeptides based on His and the unnatural (αMe)Phe have been examined as catalysts in the enantioselective addition of hydrogen cyanide to benzaldehyde and p-methoxy-benzaldehyde. The synthesis, catalytic activity and NMR study towards the mechanism of this reaction are presented.
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Doi:10.3987/COM-08-11437
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(1997)