Bioorganic and Medicinal Chemistry Letters p. 5226 - 5230 (2006)
Update date:2022-08-03
Topics:
Kazmierski, Wieslaw M.
Furfine, Eric
Spaltenstein, Andrew
Wright, Lois L.
We have developed efficient synthesis of morpholinone-based cyclic mimetics of the P1/P2 portion of the HIV-1 protease inhibitor Amprenavir. This effort led to discovery of allyl- and spiro-cyclopropyl-P2-substituted inhibitors 17 and 31, both 500 times m
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Doi:10.1021/jo9006249
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(2010)Doi:10.1016/j.bmc.2013.07.046
(2013)Doi:10.1016/S0040-4020(97)10394-5
(1998)Doi:10.1055/s-0036-1591525
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