Tetrahedron Asymmetry p. 2421 - 2432 (1997)
Update date:2022-09-26
Topics:
Herdeis, Claus
Aschenbrenner, Andrea
Kirfel, Armin
Schwabenlaender, Franz
The pyroglutamic acid derivative 4 was converted through several steps into 2S,3R,4S-epoxyproline 8. Key steps of the reaction sequence were the stereoselective epoxidation of 4 to 5 and the chemoselective reduction of the amide group of 5 with concomitan
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