New synthetic retinoids obtained by palladium-catalyzed tandem cyclisation-hydride capture process

DOI: 10.1016/S0040-4020(98)00169-0

Source and publish data:

Tetrahedron p. 4579 - 4590 (1998)

Update date:2022-08-02

Topics:

Authors:

Diaz, Philippe

Gendre, Fabrice

Stella, Lucien

Charpentier, Bruno

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Article abstract of DOI:10.1016/S0040-4020(98)00169-0

A new series of conformationally restricted retinoids (3-aryl-3-methyl- 2,3-dihydrobenzofurans) have been prepared through a palladium-catalyzed tandem cyclisation-hydride capture. The use of enantiopure BINAP-Pd catalyst allowed asymmetric synthesis of bioactive molecules.

Full text of DOI:10.1016/S0040-4020(98)00169-0

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