A short synthesis of (1S,2R)- and (1R,2R)-[1-2H]-glycerols

Article abstract of DOI:10.1016/S0957-4166(97)00219-X

A straightforward three step route to (1S,2R)- and (1R,2R)-[²H]-glycerols 1a and 1b is reported. The key asymmetric step involves an AD-mix-β dihydroxylation on deuterium labelled Z- and E-allyl benzoates 4a and 4b. The route should facilitate