Tetrahedron Letters p. 4407 - 4410 (1999)
Update date:2022-08-03
Topics:
Cocco, Maria T.
Congiu, Cenzo
Onnis, Valentina
Readily accessible fluorinated N-arylenaminones 3 were reacted with N,N- dimethylformamide dimethylacetal to produce functionalized hexadienones 4. Ring closure of 4 with ammonium acetate afforded selectively N-aryl-2- (trifluoromethyl)-4-pyridinamines 5
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