Improved synthesis and additional pharmacology of the potent analgetic (-) 5 m hydroxyphenyl 2 methylmorphan

DOI: 10.1021/jm00258a019

Source and publish data:

Journal of Medicinal Chemistry p. 1328 - 1330 (1974)

Update date:2022-08-02

Topics:

Authors:

Rogers Rogers

May May

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Article abstract of DOI:10.1021/jm00258a019

In the dimethylaminoethylation of 2 m methoxyphenylcyclohexanone an improved C:O alkyl ratio (3:4) was obtained. This combined with a better resolution procedure affords a practicable synthesis of the strong analgesic (-) 5 (m hydroxyphenyl) 2 methylmorph

Full text of DOI:10.1021/jm00258a019

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