A phosphoramidite-based synthesis of phosphoramidate amino acid diesters of antiviral nucleosides

Article abstract of DOI:10.1080/15257779408010671

A general synthetic procedure is presented for the preparation of 5'- amino acid phosphoramidates of zidovudine (AZT), 3'-deoxy-2',3'- didehydrothymidine (D4T), and 3'-fluoro-3'-deoxythymidine (FLT) from their corresponding phosphoramidites. These water s

Full text of DOI:10.1080/15257779408010671

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Nucleosides and Nucleotides
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A Phosphoramidite-Based Synthesis of
Phosphoramidate Amino Acid Diesters of
Antiviral Nucleosides
Timothy W. Abraham a & Carston R. Wagner a
a Department of Medicinal Chemistry, College of Pharmacy,
University of Minnesota Minneapolis, Minnesota, 55455, USA
Published online: 24 Sep 2006.
To cite this article: Timothy W. Abraham & Carston R. Wagner (1994): A Phosphoramidite-Based
Synthesis of Phosphoramidate Amino Acid Diesters of Antiviral Nucleosides, Nucleosides and
Nucleotides, 13:9, 1891-1903
To link to this article: http://dx.doi.org/10.1080/15257779408010671
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