Pseudomonas fluorescens lipase-catalyzed asymmetric hydrolysis and transesterification of meso-2,5-bis(acetoxymethyl)- and bis(hydroxymethyl)-3,4-(isopropylidenedioxy) tetrahydrofuran

Article abstract of DOI:10.1016/S0957-4166(97)00369-8

Pseudomonas fluorescens lipase (PFL)-catalyzed asymmetric hydrolysis of meso-2,5-bis(acetoxymethyl)-3,4-(isopropylidenedioxy) tetrahydrofuran 3 afforded the optically active monoacetate (-)-7 of high enantiomeric excess (92% ee) in 94% yield. Transesterif