Pseudomonas fluorescens lipase-catalyzed asymmetric hydrolysis and transesterification of meso-2,5-bis(acetoxymethyl)- and bis(hydroxymethyl)-3,4-(isopropylidenedioxy) tetrahydrofuran

DOI: 10.1016/S0957-4166(97)00369-8

Source and publish data:

Tetrahedron Asymmetry p. 3089 - 3094 (1997)

Update date:2022-09-26

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Authors:

Matsuo, Kenji

Tanaka, Masakazu

Sakai, Kiyoshi

Suemune, Hiroshi

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Article abstract of DOI:10.1016/S0957-4166(97)00369-8

Pseudomonas fluorescens lipase (PFL)-catalyzed asymmetric hydrolysis of meso-2,5-bis(acetoxymethyl)-3,4-(isopropylidenedioxy) tetrahydrofuran 3 afforded the optically active monoacetate (-)-7 of high enantiomeric excess (92% ee) in 94% yield. Transesterif

Full text of DOI:10.1016/S0957-4166(97)00369-8

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