Lipase-mediated resolution of trans-1-azidoindan-2-ol: A new route to optically pure cis-1-aminoindan-2-ol

DOI: 10.1055/s-1996-4328

Source and publish data:

Synthesis p. 954 - 958 (1996)

Update date:2022-09-26

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Authors:

Takahashi, Michiyasu

Ogasawara, Kunio

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Article abstract of DOI:10.1055/s-1996-4328

Optically pure trans-1-azidoindan-2-ol has been prepared in both enantiomeric forms via lipase-mediated kinetic transesterification in organic solvent. A route to optically pure cis-1-aminoindan-2-ol has also been developed by using the optically pure trans-azidoalcohol thus obtained.

Full text of DOI:10.1055/s-1996-4328

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