Synthesis of Tn, and sialyl Tn antigen-lipid a analog conjugates for synthetic vaccines

DOI: 10.1248/cpb.45.1544

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1544 - 1546 (1997)

Update date:2022-08-03

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Authors:

Miyajima, Keisuke

Nekado, Takahiro

Ikeda, Kiyoshi

Achiwa, Kazuo

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Article abstract of DOI:10.1248/cpb.45.1544

Conjugates of Tn and sialyl Tn antigen with N-teradecanoyl L-seryl-β- alanine-containing 9-glucosamine derivatives structurally related to lipid A as a immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers or HIV.

Full text of DOI:10.1248/cpb.45.1544

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