Novel azo derivatives as prodrugs of 5-aminosalicylic acid and amino derivatives with potent platelet activating factor antagonist activity

DOI: 10.1021/jm010852p

Source and publish data:

Journal of Medicinal Chemistry p. 3001 - 3013 (2001)

Update date:2022-08-03

Topics:

Authors:

Carceller

Salas Salas

Merlos Merlos

Giral Giral

Ferrando

Escamilla

Ramis Ramis

García-Rafanell

Forn Forn

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Article abstract of DOI:10.1021/jm010852p

This paper describes the synthesis of a series of azo compounds able to deliver 5-aminosalicylic acid (5-ASA) and a potent platelet activating factor (PAF) antagonist in a colon-specific manner for the purpose of treating ulcerative colitis. We found it p

Full text of DOI:10.1021/jm010852p

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