Bioorganic and Medicinal Chemistry Letters p. 2403 - 2408 (1997)
Update date:2022-09-26
Topics:
Belliotti, Thomas R.
Kesten, Suzanne R.
Rubin, John R.
Wustrow, David J.
Georgic, Lynn M.
Zoski, Kim T.
Akunne, Hyacinth C.
Wise, Lawrence D.
The dopamine D3 receptor is an attractive target for the treatment of schizophrenia. We identified PD137557 (V) as a ligand for the D2 receptor and desired to prepare a selective D3 compound. SAR studies involving different amides and different phenyl piperazines have led to the discovery of 8a and 8c as selective D3 receptor ligands.
View MoreShanghai Egoal Chemical Co.,Ltd
Contact:+86-21-50333091
Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
HANGZHOU ZHONGCHANG SCIENTIFIC CO.,LTD
Contact:+86-571-88932183
Address:Hangzhou
Contact:+86-29-88710656
Address:South Tai bai Road, High Tech Development Zone, Xi'an China
Huangshan Violet Biological Technology Co., Ltd
Contact:+86-559-2335676
Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China
Shanghai Massive Chemical Technology Co., Ltd.
website:http://www.massivechem.com/
Contact:+86 21 34943721
Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Doi:10.1002/ejoc.200900407
(2009)Doi:10.14233/ajchem.2013.13227
(2013)Doi:10.1016/j.bmcl.2004.07.001
(2004)Doi:10.1016/S0040-4039(00)94492-7
(1990)Doi:10.1016/S0040-4020(97)10292-7
(1998)Doi:10.1016/S0957-4166(97)00499-0
(1997)
