Bioorganic and Medicinal Chemistry Letters p. 2403 - 2408 (1997)
Update date:2022-09-26
Topics:
Belliotti, Thomas R.
Kesten, Suzanne R.
Rubin, John R.
Wustrow, David J.
Georgic, Lynn M.
Zoski, Kim T.
Akunne, Hyacinth C.
Wise, Lawrence D.
The dopamine D3 receptor is an attractive target for the treatment of schizophrenia. We identified PD137557 (V) as a ligand for the D2 receptor and desired to prepare a selective D3 compound. SAR studies involving different amides and different phenyl piperazines have led to the discovery of 8a and 8c as selective D3 receptor ligands.
View MoreContact:17316303296
Address:240 Amboy Ave
Contact:+86-28-88523492
Address:714rooms of Time Square, Pujiang County
Contact:+86-18653358619
Address:zibo
website:http://www.sigmaaldrich.com
Contact:800 558-9160
Address:Industriestrasse 25CH-9471 Buchs SGSwitzerland
Shandong Yubin Chemical CO.,LTD
website:http://www.yukaichem.com/en.html
Contact:+86-536-8865336
Address:binhai economic development zone，262737 shangdong，china
Doi:10.1002/ejoc.200900407
(2009)Doi:10.14233/ajchem.2013.13227
(2013)Doi:10.1016/j.bmcl.2004.07.001
(2004)Doi:10.1016/S0040-4039(00)94492-7
(1990)Doi:10.1016/S0040-4020(97)10292-7
(1998)Doi:10.1016/S0957-4166(97)00499-0
(1997)
