Synthesis of the C(11)-C(20) segment of the cytotoxic macrolide epothilone B

DOI: 10.1016/S0040-4039(97)10150-2

Source and publish data:

Tetrahedron Letters p. 7725 - 7728 (1997)

Update date:2022-08-02

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Authors:

Mulzer, Johann

Mantoulidis, Andreas

Oehler, Elisabeth

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Article abstract of DOI:10.1016/S0040-4039(97)10150-2

Compound 11, representing the C(11)-C(20) segment of the macrolide epothilone B (1b) has been prepared using two Wittig reactions and a Sharpless asymmetric epoxidation as the key steps.

Full text of DOI:10.1016/S0040-4039(97)10150-2

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