Synthesis of homo-C-D4T and homo-C-thymidine

Article abstract of DOI:10.1080/07328319708006130

β-C-Vinyl glycoside of D-arabinofuranose was converted to the β-C- hydroxymethyl glycoside 12 which was condensed with N-3-benzoyl thymine under Mitsunobu conditions to furnish homo-C-analog 14 of the 2',3'-dideoxy-2',3'- didehydrothymidine (D4T). Synthesis of the homo-C-thymidine 18 was accomplished by the same procedure from compound 15.

Full text of DOI:10.1080/07328319708006130

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Nucleosides and Nucleotides
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Synthesis of Homo-C-D4T and Homo-C-
Thymidine
Bogdan Doboszewski a b
a Department of Antibiotics , Federal University of Pernambuco ,
50739, Recife, PE, Brazil
b Department of Chemistry and Biochemistry , Brigham Young
University , Provo, UT, 84602-5700, USA
Published online: 16 Aug 2006.
To cite this article: Bogdan Doboszewski (1997) Synthesis of Homo-C-D4T and Homo-C-Thymidine,
Nucleosides and Nucleotides, 16:7-9, 1049-1052, DOI: 10.1080/07328319708006130
To link to this article: http://dx.doi.org/10.1080/07328319708006130
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