Studies toward the synthesis of popolohuanone E: Synthesis of natural (+)-arenarol related to the proposed biogenetic precursor of popolohuanone E

Article abstract of DOI:10.1016/S0040-4039(97)10075-2

The cis-fused decalin segment 6 required for the total synthesis of popolohuanone E (1) was efficiently synthesized starting from the enantiomerically pure (-)-Wieland-Miescher ketone derivative 9; the method features ortho ester Claisen rearrangement of