Synlett p. 1287 - 1290 (1997)
Update date:2022-08-04
Topics:
De Mesmaeker, Alain
Lebreton, Jacques
Jouanno, Chantal
Fritsch, Valérie
Wolf, Romain M.
Wendeborn, Sebastian
The amide backbone modification C3′-CH2-CONH-C5′ has been further modified by introducing a methyl at C5′, either in R or in S configuration. Only the S stereoisomer can adopt the required geometry to fit into a duplex with complementary RNA. A
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(2019)
