
Tetrahedron Letters p. 8265 - 8266 (1997)
Update date:2022-08-04
Topics:
Fains, Olivier
Vernon, John M.
In 2-(2-hydroxy-1-phenylethyl)-1-isoindolinone, selective removal of the 2-hydroxy-1-phenylethyl group is conveniently achieved via a 3-step sequence (mesylation, elimination, hydrolysis) without breaking an endocyclic benzylic nitrogen bond.
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