Journal of Organic Chemistry p. 7348 - 7350 (1995)
Update date:2022-08-03
Topics:
Olah, George A.
Orlinkov, Alexander
Oxyzoglou, Alexandros B.
Prakash, G. k. Surya
The nitration of various deactivated arenes (including methanesulfonyl-, nitro-, and polyhalobenzenes) was carried out in good yield with mixed nitric-triflatoboric superacid.For example pentafluorobenzene gave pentafluoronitrobenzene in 99percent yield, nitrobenzene to m-dinitrobenzene in 92percent selectivity with 85percent overall yield, and methyl phenyl sulfone gave only the m-nitro isomer in 78percent isolated yield.Thus the new nitrating system gives high regioselectivity and yields under generally mild reaction conditions.The reagent system is compatible with many functional groups of arenes.
View MoreLaizhou City Laiyu Chemical CO.,Ltd
Contact:+86-535-2719337/2719339
Address:Chenggang road zhuyou laizhou City Shangdong China
Shandong Xiangde Biotechnology Co., Ltd
Contact:+86 -15066639877
Address:Sanba street
Zouping Mingxing Chemical Co.,Ltd.
website:http://www.zoutong.com.cn
Contact:86-543-2240068 2240067
Address:428 Daixi Third Road Zouping County Shandong Province China
Dalian Join King Biochemical Tech. Co., Ltd.
Contact:0411 39216206
Address:814 First State Blvd
Chengda Pharmaceuticals Co., Ltd.
Contact:+86-573-84601188
Address:hengshan Road 5# in Jiashan, zhejiang
Doi:10.1002/ejoc.201901827
(2020)Doi:10.1055/S-0032-1317157
(2012)Doi:10.1002/cbic.201200350
(2012)Doi:10.1016/j.tet.2019.05.033
(2019)Doi:10.1021/ml3003605
(2013)Doi:10.1016/j.tet.2012.11.040
(2013)