Journal of Heterocyclic Chemistry p. 1493 - 1496 (1994)
Update date:2022-08-03
Topics:
Bolos
Gubert
Anglada
Perez
Sacristan
Ortiz
The synthesis of the novel amino acid 6-(hydroxymethyl)-2-piperidinecarboxylic acid (1a) and its ethyl ester 1b is reported. In the hydrogenation of 6-(hydroxymethyl)pyridine-2-carboxylates, hydrogenolysis of the alcohol group appeared as an unusual side reaction. Optimization of the reaction conditions allowed us to minimize hydrogenolysis and afforded pure 1.
View MoreSuzhou Howsine Biological Technology Co.,Ltd(expird)
website:http://www.howsine.com
Contact:86-512-67262751
Address:No 3,Weihua Road ,Suzhou Industrial Park ,Jiangsu ,China.
Nanjing Fayekong Chemcial Co.,Ltd(expird)
Contact:86-25-58813444
Address:Rm 1503, Unit 1, Building 5, Zijinnanyuan, Nanjing, Jiangsu, China
Contact:+1 (647) 918 5848
Address:2343 BRIMLEY RD., Suite 250
Hubei Lansun Biochemical Pharmaceutical Co., Ltd
Contact:714-6395977
Address:No. 81 Pengcheng Avenue, economic and technological development zone, Huangshi City, Hubei Province,China
Shandong Yuanli Science and Technology Co., Ltd.
Contact:86-0536-6777557
Address:Zhuliu Industiral Park,Changle County
Doi:10.1039/DT9950002923
(1995)Doi:10.1021/jo060129c
(2006)Doi:10.1021/acschembio.9b00289
(2019)Doi:10.1021/jacs.1c01483
(2021)Doi:10.1246/bcsj.61.2773
(1988)Doi:10.1016/S0040-4020(97)10141-7
(1997)
