The palladium catalyzed allylic alkylation of bis(trimethylsilyl) substituted propenyl acetates or carbonates in the presence of chiral ligands

Article abstract of DOI:10.1016/S0040-4039(97)10380-X

Palladium catalyzed asymmetric allylic alkylations of a bis(trimethylsilyl) substituted propenyl acetate and carbonate were investigated using various chiral ligands and reaction conditions. The best enantioselectivity (86% e.e.) was obtained with the substrate 1-phenyl-3,3-bis(trimethylsilyl)propenyl carbonate 13 and the chiral oxazoline ligand 4c.