Synthesis and ring-chain tautomerism of angularly substituted cycloalkane-fused tetrahydro-1,3-oxazines

Article abstract of DOI:10.1016/S0040-4020(97)10355-6

Starting from 1-methyl-1-cyclopentene and -cyclohexene, regioisomeric 1,3-amino alcohols 6a,b and 7a,b were prepared by regio- and stereospecific reactions. When the amino alcohols were condensed with aromatic aldehydes, well-defined products 8-11 were ob