Syntheses and antifungal activity of dl-griseofulvin and its congeners. III

DOI: 10.1248/cpb.45.2011

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2011 - 2015 (1997)

Update date:2022-08-04

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Authors:

Takeuchi, Yasuo

Watanabe, Ikuo

Misumi, Keiji

Irie, Mari

Hirose, Yoko

Hirata, Kazumi

Yamato, Masatoshi

Harayama, Takashi

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Article abstract of DOI:10.1248/cpb.45.2011

Several congeners (1b-g), with novel substituents on the benzene ring of griseofulvin, were prepared by the application of a synthetic method developed by us. Antifungal activity of these congeners decreased in order of dl-griseofulvin (1a)=1d > 1b, c >>

Full text of DOI:10.1248/cpb.45.2011

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