Chemical and Pharmaceutical Bulletin p. 2011 - 2015 (1997)
Update date:2022-08-04
Topics:
Takeuchi, Yasuo
Watanabe, Ikuo
Misumi, Keiji
Irie, Mari
Hirose, Yoko
Hirata, Kazumi
Yamato, Masatoshi
Harayama, Takashi
Several congeners (1b-g), with novel substituents on the benzene ring of griseofulvin, were prepared by the application of a synthetic method developed by us. Antifungal activity of these congeners decreased in order of dl-griseofulvin (1a)=1d > 1b, c >>
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