Efficient synthesis and gastric (H+/K+)-ATPase-inhibitory activity of 2-aryl-4,5-dihydro-1H-thieno[3,2-e]benzimidazoles

DOI: 10.1248/cpb.45.1945

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1945 - 1954 (1997)

Update date:2022-08-05

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Authors:

Homma, Koichi

Watanabe, Tatsuya

Iijima, Toru

Yato, Michihisa

Matsuki, Kenji

Noto, Tsunehisa

Ishida, Akihiko

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Article abstract of DOI:10.1248/cpb.45.1945

A series of 2-aryl-4,5-dihydro-1H-thieno[3,2-e]benzimidazoles (1, 2) was prepared by condensation of 5-acylamino-4,5,6,7-tetrahydrobenzo[b]thiophen- 4-ones (9, 10) with ammonium acetate under azeotropic reaction conditions. Various congeners, N-methyl and

Full text of DOI:10.1248/cpb.45.1945

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