Bioorganic and Medicinal Chemistry Letters p. 3033 - 3038 (1997)
Update date:2022-08-05
Topics:
Balakrishnan
Gilbert
Brueggemeier
Curley Jr.
Glucuronide conjugates of retinoids have been found to be active metabolites of the parent molecules. However, O-acylglucuronide retinoids are liable to hydrolysis and retinoid ring oxidation. We have prepared stable N-linked glycosides of acitretin in efforts to overcome these problems. The synthesis and preliminary biological studies of the analogs are reported.
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Doi:10.1016/S0223-5234(97)82774-2
(1997)Doi:10.1039/a800108a
(1998)Doi:10.1016/S0022-328X(97)00278-7
(1997)Doi:10.1039/a704141a
(1997)Doi:10.1039/c8cc08594c
(2019)Doi:10.1271/bbb.61.2019
(1997)
