Synthesis of methyl D- and L-glycero-α-D-manno-heptofuranosides

Article abstract of DOI:10.1016/S0008-6215(97)00269-3

Methyl L-glycero-α-D-manno- and D-glycero-α-D-manno-heptofuranosides (1 and 2) have been synthesized using two-carbon-atom elongation of a lyxofuranoside system. A new method for the synthesis of 2 has been developed based on the reaction of protected methyl α-D-manno-hexodialdo-1,4-furanoside with benzyloxymethylmagnesium chloride.