Synthesis of the hexasaccharide fragment of landomycin A: Application of glycosyl tetrazoles and phosphites in the synthesis of a deoxyoligosaccharide

Article abstract of DOI:10.1021/ja973348b

The synthesis of the hexasaccharide fragment of the antitumor antibiotic landomycin A (1) (aka. NSC 639187) is described. The stereocontrolled introduction of key glycoside linkages relies on the combined application of glycosyl tetrazoles and phosphites