Synthesis and biological evaluation of flavanones and flavones related to podophyllotoxin

DOI: 10.1248/cpb.46.79

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 79 - 83 (1998)

Update date:2022-07-31

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Authors:

De Peredo, Anne Gonzalez

Léonce, Stéphane

Monneret, Claude

Dauzonne, Daniel

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Article abstract of DOI:10.1248/cpb.46.79

A series of novel flavonoids comprising structural elements present in the antineoplastic agents podophyllotoxin and etoposide was synthesized. These oxygen-containing analogues of antiproliferative quinolones exhibited moderate cytotoxicity towards L1210 and HT-29 cell lines.

Full text of DOI:10.1248/cpb.46.79

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