Bioorganic and Medicinal Chemistry Letters p. 1161 - 1166 (1999)
Update date:2022-08-02
Topics:
Petitou, Maurice
Driguez, Pierre-Alexandre
Duchaussoy, Philippe
Herault, Jean-Pascal
Lormeau, Jean-Claude
Herbert, Jean-Marc
A synthetic heptadecasaccharide, comprising an antithrombin III binding domain, a thrombin binding domain, and a neutral methylareal hexasaccharide sequence, was obtained through a convergent synthesis. This compound displayed in vitro anticoagulant properties similar to that of standard heparin but, in contrast with heparin, escaped neutralization by platelet factor 4, a protein released by activated platelets.
View MoreTaizhou Shengxing Chempharm Co.,Ltd
Contact:+86-576-88516600
Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Jiaxing Carry Bio-Chem Technology Co.,Ltd
website:http://www.carrybiotech.com
Contact:0573-82788958
Address:Add.Fl 3th, Pharm Vally,Kaichuang Rd, Xiuzhou District, Jiaxing, Zhejiang,314031,China
Contact:+86-27-67841589
Address:Add: 999 Gaoxin Road, Donghu New Technology Development Zone, Wuhan City, Hubei, China
Shanghai Dano Pharmaceutical Co.,Ld.(expird)
Contact:+86-592-6266840
Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
Contact:+86-571-87010026
Address:202, Zhenhua Road,
Doi:10.1016/j.tetlet.2007.01.055
(2007)Doi:10.1016/0040-4020(65)80016-3
(1965)Doi:10.1016/S0960-894X(97)10203-7
(1998)Doi:10.1002/anie.200504468
(2006)Doi:10.1016/S0040-4039(98)00085-9
(1998)Doi:10.1021/ic50005a039
(1963)
