Nucleosides and Nucleotides p. 1671 - 1679 (1998)
Update date:2022-08-03
Efimov, Vladimir A.
Choob, Michael V.
Buryakova, Alla A.
Chakhmakhcheva, Oksana G.
The preparation of monomers for the synthesis of phosphonate analogues of peptide nucleic acids containing the four natural nucleobases: thymine, cytosine, adenine and guanine, has been accomplished. The monomers obtained were used for the automated online solid phase synthesis of pure phosphono- PNA oligomers as well as chimeras consisting of phosphono-PNA and PNA resudies. The hybridization properties of these oligonucleotide mimics to complementary DNA and RNA fragments were studied.
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Doi:10.1002/(sici)1521-3749(199803)624:3<443::aid-zaac443>3.0.co;2-a
(1998)Doi:10.1016/S0040-4020(98)00008-8
(1998)Doi:10.1055/s-0028-1216726
(2009)Doi:10.1016/S0022-2860(00)00693-1
(2001)Doi:10.1021/jm980545s
(1999)Doi:10.1002/prac.19983400213
(1998)