Synthesis of substituted imidazo[4,5-b]pyridines as analogues of the DNA binding fluorochrome Hoechst 33258

Article abstract of DOI:10.1080/00397919808004966

Various substituted imidazo[4,5-b]pyridine analogues of Hoechst 33258 have been synthesized to explore the potential of selective helicase blockade and anticancer activity. The target compounds II a, b and d were obtained by condensation of the appropriate functionalized diamine and substituted benzimidazole aldehydes in nitrobenzene.

Full text of DOI:10.1080/00397919808004966

Synthetic Communications
ISSN: 0039-7911 (Print) 1532-2432 (Online) Journal homepage: http://www.tandfonline.com/loi/lsyc20
Synthesis of Substituted Imidazo[4,5-b]pyridines
as Analogues of the DNA Binding Fluorochrome
Hoechst 33258
Ashok K. Singh & J. WilliamLown
To cite this article: Ashok K. Singh & J. WilliamLown (1998) Synthesis of Substituted
Imidazo[4,5-b]pyridines as Analogues of the DNA Binding Fluorochrome Hoechst 33258,
Synthetic Communications, 28:21, 4059-4066, DOI: 10.1080/00397919808004966
To link to this article: http://dx.doi.org/10.1080/00397919808004966
Published online: 16 Aug 2006.
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Date: 03 June 2016, At: 07:34