Tetrahedron Letters p. 1185 - 1188 (1998)
Update date:2022-07-29
Topics:
Tanaka, Katsunori
Kamatani, Mitsunobu
Mori, Hajime
Fujii, Shinobu
Ikeda, Kiyoshi
Hisada, Miki
Itagaki, Yasuhiro
Katsumura, Shigeo
3-(E)Methoxycarbonyl-2,4,6-trienal compound A was stereoselectively synthesized and found to show strong inhibitory activity toward phospholipase A2 (PLA2) from bovine pancreas. As the inhibitory mechanism of PLA2 by A, the irreversible formation of dihydropyridine resulting from the reaction of A with lysine residues in PLA2 is proposed based on the model reactions.
View MoreJiangxi Dongxu Chemical Science & Technology Co.,Ltd
Contact:+86-791-86899381
Address:Nanchang, Jiangxi, China
website:http://www.herbpurify.com
Contact:0086-028-85249238
Address:Room709-C1,Incubator Building, Tianfu Life Science Park No.88,Keyuan Road,Gaoxin district,Chengdu City,Sichuan Prov,China
Suzhou CarbonWell Pharma-Tech Co., Ltd
Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602
Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Shanghai Kefu Chemical Co.,Ltd.
Contact:+86-21-34616196
Address:Room601-602, Xuhui Business Building, No.168, Yude Road, Shanghai
Doi:10.1021/ja9801543
(1998)Doi:10.1055/s-1998-1609
(1998)Doi:10.1002/(SICI)1099-0682(199802)1998:2<245::AID-EJIC245>3.0.CO;2-T
(1998)Doi:10.1021/jo990464j
(1999)Doi:10.1021/ja01016a074
(1968)Doi:10.1016/S0040-4039(01)99090-2
(1968)
