New methodology for the synthesis of α,α-dialkylamino acids using the "self-regeneration of stereocenters" Method: α-ethyl-α-phenylglycine

Article abstract of DOI:10.3987/com-97-s83

The stereoselective room temperature ethylations of protected oxazolidinones from phenylglycine by phase-transfer catalysis or with KOtBu as base are used to prepare optically active α-ethyl-α-phenylglycine.