A novel and enantioselective approach to the synthesis of cyclohexane carbocyclic nucleosides starting from (-)-carvone

Article abstract of DOI:10.1080/15257779908041504

3,5-dihydroxy-4-(hydroxymethyl)-1-cyclohexanyl adenine has been synthesized starting from (-)-carvone. The adenine base was introduced via Mitsunobu reaction. Conformational analysis showed that the base still adopts the equatorial position at the expense of three axial substituents.

Full text of DOI:10.1080/15257779908041504

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Nucleosides and Nucleotides
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A Novel and Enantioselective Approach
to the Synthesis of Cyclohexane
Carbocyclic Nucleosides Starting from
(-)-Carvone
Jing Wang a & Piet Herdewijn a
a Laboratory of Medicinal Chemistry , Rega Institute for Medical
Research, K. U. Leuven , Minderbroedersstraat 10, B-3000, Leuven,
Belgium
Published online: 04 Oct 2006.
To cite this article: Jing Wang & Piet Herdewijn (1999) A Novel and Enantioselective Approach to
the Synthesis of Cyclohexane Carbocyclic Nucleosides Starting from (-)-Carvone, Nucleosides and
Nucleotides, 18:4-5, 591-592, DOI: 10.1080/15257779908041504
To link to this article: http://dx.doi.org/10.1080/15257779908041504
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