Bioorganic and Medicinal Chemistry Letters p. 433 - 436 (1998)
Update date:2022-09-26
Topics:
Fernandez-Garcia, Concepcion
Prager, Kai
McKervey, M. Anthony
Walker, Brian
Williams, Carvell H.
α-Keto-β-aminoacids 5a-c can be reductively aminated with the peptide sequence H2N-Leu-Val-Phe-Phe on a solid support to afford N-carboxy alkyl peptides 1a-c. The N-carboxy alkyl lysine derivative 7 was subsequently extended from the N-terminus with glutamine and histidine residues.
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Doi:10.1039/a709082j
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