Synthesis and antiproliferative activity of 3-substituted 1H-indole [3,2-d]-l,2,3-triazin-4 (3H)-ones

DOI: 10.1016/S0223-5234(99)80074-9

Source and publish data:

European Journal of Medicinal Chemistry p. 43 - 46 (1998)

Update date:2022-09-26

Topics:

Authors:

Garuti, Laura

Roberti, Marinella

Rossi, Tiziana

Castelli, Mario

Malagoli, Monica

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Article abstract of DOI:10.1016/S0223-5234(99)80074-9

Some 3-substituted indole-triazin-4-ones were synthesized. Their antiproliferative activity against chronic myeloid leukaemia and non-Hodgkin lymphoma human cells was compared in vitro with that of daunorubicin. One compound appeared to be very effective against human CML.

Full text of DOI:10.1016/S0223-5234(99)80074-9

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