Synthesis and antiproliferative activity of 3-substituted 1H-indole [3,2-d]-l,2,3-triazin-4 (3H)-ones

Article abstract of DOI:10.1016/S0223-5234(99)80074-9

Some 3-substituted indole-triazin-4-ones were synthesized. Their antiproliferative activity against chronic myeloid leukaemia and non-Hodgkin lymphoma human cells was compared in vitro with that of daunorubicin. One compound appeared to be very effective against human CML.