Stability and structural features of the duplexes containing nucleoside analogues with a fixed N-type conformation, 2'-O,4'-C- methyleneribonucleosides

DOI: 10.1016/S0040-4039(98)01084-3

Source and publish data:

Tetrahedron Letters p. 5401 - 5404 (1998)

Update date:2022-09-26

Topics:

Authors:

Obika, Satoshi

Nanbu, Daishu

Hari, Yoshiyuki

Andoh, Jun-Ichi

Morio, Ken-Ichiro

Doi, Takefumi

Imanishi, Takeshi

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Article abstract of DOI:10.1016/S0040-4039(98)01084-3

Bicyclic nucleoside analogues with a fixed N-type conformation, 2'- O,4'-C-methyleneuridine and -cytidine, were incorporated into oligonucleotides, and the binding efficiency of the modified oligonucleotides to the complementary DNA and RNA as well as the

Full text of DOI:10.1016/S0040-4039(98)01084-3

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