An enantiospecific cobaloxime π-cation initiated carbocyclisation

Article abstract of DOI:10.1016/S0040-4039(98)00163-4

The cationic carbocyclisation of the allyl silane substituted β-hydroxycobaloxime (+)-4 was effected by treatment with catalytic amounts of pTSA to form the cyclopentane derivative (+)-5 which was elaborated to the aldehyde (-) 7 via the alcohol (-)-6. Bo