Glycosidopyrroles. Part 1. Acyclic derivatives: 1-(2-hydroxyethoxy) methylpyrroles as potential anti-viral agents

DOI: 10.1016/S0014-827X(97)00002-5

Source and publish data:

Il Farmaco p. 33 - 40 (1998)

Update date:2022-07-31

Topics:

Authors:

Almerico, Anna Maria

Diana, Patrizia

Barraja, Paola

Dattolo, Gaetano

Mingoia, Francesco

Loi, Anna Giulia

Scintu, Franca

Milia, Carlo

Puddu, Ivana

La Colla, Paolo

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Article abstract of DOI:10.1016/S0014-827X(97)00002-5

Acyclic glycosidopyrroles of type 1, synthesized in good overall yields, were evaluated for anti-viral activity. Compound 10i was found to inhibit the HIV-1 replication at concentrations that were very close to those cytotoxic for MT-4 cells. Compounds 10

Full text of DOI:10.1016/S0014-827X(97)00002-5

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Product name:1-(2-Acetoxyethoxy)methyl-2,5-diphenyl-3-ethoxycarbonyl-4-nitropyrrole

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