Synthesis of benzylated (R)- and (S)-aminoethyl-C-α-D-mannosides as conformationally restricted building blocks for the preparation of E- and P- selectin antagonists

Article abstract of DOI:10.1016/S0040-4039(98)00342-6

A straightforward synthesis for the aminoethyl-C-α-D-mannosides (R)-1 and (S)-1 has been developed. The conformationally restricted mannosides serve as building blocks for the synthesis of a new class of selectin antagonists of type A.