Medicinal Chemistry Research p. 220 - 235 (2010)
Update date:2022-08-03
Topics:
Benaka Prasad
Vinaya
Ananda Kumar
Swarup, Sanjay
Rangappa
A series of novel diphenyl(piperidin-4-yl)methanol derivatives 10(a-n) were synthesized and characterized by 1H NMR, LC/MS, FTIR, and elemental analyses. All the synthesized compounds were evaluated for cell proliferation by MTT assay. The antiproliferative effects of the synthesized compounds were tested against viable human skin fibroblast cell line and carcinoma cell lines, namely HeLa cells, HT-29 cells, MCF-7 cells, and HepG-2 cells in comparing the positive and negative control. Among the synthesized compounds, (10b) and (10g) have been identified as potent antiproliferative agents.
View Morewebsite:http://www.mingchem.com/en/index
Contact:0519-85170101-802
Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Chengdu Push Bio-technology Co., Ltd
Contact:86-28-85370565
Address:No.8 Wuke West Second Road, Wuhou
Contact:+8613400661290
Address:No 908,Kangwan Rd, Liuyang Economic
Shandong Loyal Chemical industrial Co.,Ltd
Contact:0533-7451788
Address:Linzi Chemical Industrial Park, Zibo, Shandong Province
Shandong Xinhua Pharmaceutical Co.,Ltd
website:http://www.xhzy.com
Contact:+86-533-2196801
Address:1 lutai road,zhangdian dis,Zibo City
Doi:10.1021/bc2001038
(2011)Doi:10.1021/ol202315m
(2011)Doi:10.1016/S0022-1139(00)80292-4
(1991)Doi:10.1016/S0040-4039(00)74875-1
(1991)Doi:10.1002/hlca.19910740106
(1991)Doi:10.1016/0040-4039(90)80195-R
(1990)