Retinoid X receptor-antagonistic diazepinylbenzoic acids

DOI: 10.1248/cpb.47.1778

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1778 - 1786 (1999)

Update date:2022-08-02

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Authors:

Ebisawa, Masayuki

Umemiya, Hiroki

Ohta, Kiminori

Fukasawa, Hiroshi

Kawachi, Emiko

Christoffel, Ghislaine

Gronemeyer, Hinrich

Tsuji, Motonori

Hashimoto, Yuichi

Shudo, Koichi

Kagechika, Hiroyuki

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Article abstract of DOI:10.1248/cpb.47.1778

Several dibenzodiazepine derivatives were identified as novel retinoid X receptor (RXR) antagonists on the basis of inhibitory activity on retinoid- induced cell differentiation of human promyelocytic leukemia cells HL-60 and transactivation assay using r

Full text of DOI:10.1248/cpb.47.1778

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