
Tetrahedron Letters p. 3099 - 3102 (1998)
Update date:2022-07-30
Topics:
Davis, Franklin A.
Andemichael, Yemane W.
A general approach to enantiomerically pure 3-substituted-1(2H)- isoquinolones is illustrated by the addition of lateral lithiated amide 7 to sulfinimine 5. Isoquinolone 8 is readily transformed into (3R,4S)-(-)-4- hydroxy-3-phenyltetrahydroisoquinoline 15 via hydroxylation and reduction.
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Doi:10.1016/S0040-4039(98)00734-5
(1998)Doi:10.1055/s-1998-867117
(1998)Doi:10.1007/BF01169898
()Doi:10.1135/cccc19980590
(1998)Doi:10.1016/j.tet.2008.09.098
(2008)Doi:10.1021/jm010888h
(2001)