A stereoselective one-pot synthesis of perhydro-7a-hydroxy-7- phenylthiofurano[3,2-b]pyran via an acid-catalysed deprotection/double cyclisation/rearrangement sequence

Article abstract of DOI:10.1016/S0040-4039(98)00560-7

Treatment of 1,3-bis-(tert-butyldimethylsilyloxy)ethyl]-1- phenylsulfinyl-1,2-propadiene with aqueous HF in acetonitrile led to the formation of the tide compound as one diastereoisomer (from NMR analysis). The reaction was carried out under thermodynamic