Synthesis of DNA analogues with novel carboxamidomethyl phosphonamide and glycinamide internucleoside linkages

DOI: 10.1016/S0960-894X(98)00153-X

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1013 - 1018 (1998)

Update date:2022-07-29

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Authors:

Efimov Efimov

Buryakova

Chakhmakhcheva

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Article abstract of DOI:10.1016/S0960-894X(98)00153-X

Thymidine oligonucleotide analogues with phosphodiester bonds fully substituted by carboxamidomethyl phosphonamide, or glycinamide linkages were synthesized on a solid support, and their hybridization properties toward DNA and RNA targets were determined by Tm analysis.

Full text of DOI:10.1016/S0960-894X(98)00153-X

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